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(Centro Nacional de Investigaciones Oncologicas (CNIO)) CNIO researcher Manuel Serrano, one of the world's leading experts on senescence, publishes a review on this topic. Without actually renaming this term, this edition of Nature Reviews promotes a paradigm shift: senescence is, above all, 'a mechanism to eliminate unwanted cells', which ends with the remodelling of tissues. And it can be something of a double-edged sword for the body.
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